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EAGLE - Research project
Eye Anterior segment Laser Engineering
ABSTRACT
The eye and the femtosecond laser have long been closely linked. Yesterday, in the United States, the cutting of LASIK caps for myopia was born, with the success that we know. Today, photo-emulsification™ of the lens for cataract surgery was born in France (first patient operated at the end of 2018).
The EAgLE project, bringing together the BiiO, the Hubert Curien Laboratory and the Manutech-USD technical platfrom, proposes two new applications of the laser to the anterior segment of the eye (cornea and lens) to offer an answer to the major challenges of tomorrow.
Corneal re-engineering, thanks to laser cutting and then surfacing of corneas rejected from banks or lens capsules, will combat the global shortage of grafts (in collaboration with the Japanese team in Kyoto, specialising in cell cultures). Modification of the biomechanics of the lens which, with a multi-scale laser technology, will offer the first etiological and non-invasive treatment of presbyopia (collaboration with the Kejako start-up, based in St-Etienne).
The EAgLE project, bringing together the BiiO, the Hubert Curien Laboratory and the Manutech-USD technical platfrom, proposes two new applications of the laser to the anterior segment of the eye (cornea and lens) to offer an answer to the major challenges of tomorrow.
Corneal re-engineering, thanks to laser cutting and then surfacing of corneas rejected from banks or lens capsules, will combat the global shortage of grafts (in collaboration with the Japanese team in Kyoto, specialising in cell cultures). Modification of the biomechanics of the lens which, with a multi-scale laser technology, will offer the first etiological and non-invasive treatment of presbyopia (collaboration with the Kejako start-up, based in St-Etienne).
CONFERENCES
- Ben Moussa O, Talbi A, Gain P, Thuret G, Xxx S, Mauclair C. Histological and in situ microscopic observation of femtosecond laser induced incisions in the crystalline lens. Procédés Laser pour l'Industrie Saint-Etienne 28-29 juin 2022 (PLI 2022)
- Ben Moussa O, Talbi A, Gain P, Thuret G, Xxx S, Mauclair C. Histological and in situ microscopic observation of femtosecond laser induced incisions in the crystalline lens. ALT 2021, Moscow, Russia, Sept. 2021
PUBLICATIONS
- Olfa Ben Moussa, Abderazek Talbi, Sylvain Poinard, Thibaud Garcin, Anne-Sophie Gauthier, Gilles Thuret, Philippe Gain, Aurélien Maurer, Xxx Sedao, and Cyril Mauclair. 2022. "Characterization of Femtosecond Laser and Porcine Crystalline Lens Interactions by Optical Microscopy" Micromachines 13, no. 12: 2128.
https://doi.org/10.3390/mi13122128
ABOUT the EAGLE project
RESEARCH AXIS
Axis #3
KEYWORDS
Femtosecond laser, Anterior segment of the eye, Tissue engineering, Corneal grafting, Presbyopia
DURATION - STATUS
16/12/2019 – 01/03/2022 - Completed
POST-DOCTORAL FELLOW
Abderazek TALBI (BiiO)
Olfa BEN MOUSSA (BiiO)
PROJECT COORDINATOR
Philippe GAIN (BiiO)
COORDINATING LABORATORY
BIIO Laboratory (BIIO)
PARTNER LABORATORIES - OTHER PARTNERS
Hubert Curien Laboratory (LabHC)
EquipEx Manutech-USD
Université Doshida (Kyoto, Japan)
Kejako company (Saint-Etienne)
PARTNER RESEARCHERS - OTHER PARTNERS
Gilles THURET (BiiO)
Emilie COURRIER (BiiO)
Samy ALBOURGOL (BiiO)
HE Zhiguo (BiiO)
Cyril MAUCLAIR (LabHC)
KOIZUMI Noriko (Université Doshida)
David ENFRUN (Kejako)
Axis #3
KEYWORDS
Femtosecond laser, Anterior segment of the eye, Tissue engineering, Corneal grafting, Presbyopia
DURATION - STATUS
16/12/2019 – 01/03/2022 - Completed
POST-DOCTORAL FELLOW
Abderazek TALBI (BiiO)
Olfa BEN MOUSSA (BiiO)
PROJECT COORDINATOR
Philippe GAIN (BiiO)
COORDINATING LABORATORY
BIIO Laboratory (BIIO)
PARTNER LABORATORIES - OTHER PARTNERS
Hubert Curien Laboratory (LabHC)
EquipEx Manutech-USD
Université Doshida (Kyoto, Japan)
Kejako company (Saint-Etienne)
PARTNER RESEARCHERS - OTHER PARTNERS
Gilles THURET (BiiO)
Emilie COURRIER (BiiO)
Samy ALBOURGOL (BiiO)
HE Zhiguo (BiiO)
Cyril MAUCLAIR (LabHC)
KOIZUMI Noriko (Université Doshida)
David ENFRUN (Kejako)